Presented by: Michael Edwards, Ph.D. Assistant Professor Division of Pulmonary Science and Critical Care Medicine. University of Colorado, Denver | Duration: 40:13 minutes

This webinar discusses an important antitumor pathway in lung cancer (Wnt7a signaling) as a framework to explain the bioinformatic analysis process using IPA. Topics covered include biological function and pathway analysis, network construction, and identifying and interpreting upstream regulators.

Presented by: Dr. Walter Bottje, Professor, Dept. of Poultry Science, University of Arkansas | Duration: 41:26 minutes

Global RNA expression in breast muscle obtained from a male broiler line phenotyped for high or low feed efficiency (FE) was investigated using microarray analysis. By using an overlay function of IPA in which canonical pathways can be projected onto … Read More

Presented by: Aimee Jackson, Ph.D. | Duration: 23:09 minutes

microRNAs are small, non-coding RNAs that function as central regulators of gene expression and development. These regulatory molecules have been implicated in a wide range of normal and pathological activities, including embryonic development, cancer, inflammation, cardiovascular disease and viral infections. … Read More

Presented by: Christopher E. Mason, Ph.D., Assistant Professor, Department of Physiology and Biophysics and the Institute for Computational Biomedicine; Affiliate Fellow of Genomics, Ethics, and Law, ISP, Yale Law School | Duration: 37:16 minutes

Learn how to use Ingenuity® Variant Analysis™ to analyze whole genome sequencing data. Chris Mason, Ph.D., presents a case study where Variant Analysis was used to analyze data from rare clinical cases with extreme phenotypes from the NIH’s Undiagnosed Disease … Read More

Presented by: Simo Arredouani, Assistant Professor of Surgery at Harvard Medical School | Duration: 45:00 minutes

The inhibitory role of regulatory T-cells (Tregs) in cancer is now well established. Furthermore, inhibition of Treg function has been shown both experimentally and clinically to improve the immune response towards a variety of cancers. Developing new and more effective … Read More

Presented by: Dr. Jochen Danny Muehlschlegel, M.D., Harvard Medical School | Duration: 36:23 minutes

See how IPA was used for the discovery of novel pathways of affected genes in coronary artery disease. Cardiopulmonary bypass (CPB) with cardioplegic arrest is associated with ischemia leading to metabolic substrate depletion, reperfusion injury, apoptosis and necrosis. The study … Read More

Presented by: Jean-Noel Billaud, Ph.D., QIAGEN Silicon Valley and and Sylvain Foissac, Ph.D., Integromics | Duration: 58:00 minutes

The Ewing’s Sarcoma family of tumors is a category of cancers that predominantly affects teenagers between the ages of 10 to 20. Learn how QIAGEN Silicon Valley’ IPA software and Integromics’ SeqSolve software were used to investigate Ewing’s Sarcoma patient … Read More

Presented by: Darryl Gietzen, Ph.D., QIAGEN Silicon Valley | Duration: 33:44 minutes

IPA was used to interpret Alzheimer’s disease biology by comparing Illumina RNA-Seq data from Alzheimer’s disease (AD) and normal brain samples. This analysis revealed very specific biological changes in certain classes of transcript expression, demonstrating how the unique benefits of … Read More

Presented by: Dr. Prysak | Duration: 18:29 minutes

Learn how Dr. Prysak utilized IPA to investigate the neuropathic pathways related to pain. In the United States, more than 39 million people suffer from neuropathic pain related to postherpetic neuralgia, trigeminal neuralgia, AIDS-related neuropathy, diabetic neuropathy, chronic low back … Read More